Childrens Panadol 5 - 12 Years

Thursday, October 30, 2008
acetaminophen (oral/ rectal)



Pronunciation: a see ta MIH no fen
Brand: Anacin-3 Maximum Strength, Childrens Tylenol, Tylenol, Tylenol Caplet, Tylenol Caplet Extra Strength, Tylenol Extended Release, Tylenol Extra Strength, Tylenol Gelcap Extra Strength, Tylenol Suspension


What is the most important information I should know about acetaminophen?

Use acetaminophen for up to 3 days for fever or up to 10 days for pain (or up to 5 days to treat a child's pain). If the symptoms do not improve, or if they get worse, stop using acetaminophen and see a doctor.
Avoid alcohol during treatment with acetaminophen. Together, alcohol and acetaminophen can be damaging to the liver.

Be aware of the acetaminophen content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.


What is acetaminophen?

Acetaminophen is a pain reliever and a fever reducer.

Acetaminophen is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.

Acetaminophen may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking acetaminophen?
Do not take acetaminophen without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease. You may not be able to take acetaminophen, or you may require a lower dose or special monitoring.

Before taking acetaminophen, tell your doctor if you have kidney or liver disease. You may not be able to take acetaminophen, or you may require a dosage adjustment or special monitoring during treatment if you have either of these conditions.

Acetaminophen has not been formally assigned to a pregnancy category by the FDA. It is routinely used for short term pain relief and fever in all stages of pregnancy. Acetaminophen is believed to be safe in pregnancy when used intermittently for short durations. Acetaminophen should only be given during pregnancy when need has been clearly established.

Acetaminophen passes into breast milk. It appears to be safe for use during breast-feeding but should be avoided if possible. Talk to your doctor before taking acetaminophen if you are breast-feeding a baby.

If you are treating a child, read the package carefully and use a pediatric form of the medication if possible. Talk to a doctor first if the child is younger than 2 years of age.


How should I take acetaminophen?

Take acetaminophen exactly as directed by your doctor or follow the instructions on the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each oral dose with a full glass of water.

Acetaminophen can be taken with or without food.
Wash your hands before and after using the rectal suppositories. Run the suppository under cold water or put it in the refrigerator for a few minutes before using it. Remove any wrapping from the suppository and moisten the suppository with cold water. Squat, stand, or lie down with one leg straight and the other bent, in a comfortable position that allows access to the rectal area. Use your finger, or the applicator if one is provided, to deposit the suppository as far as it will comfortably go into the rectum. Insert the narrow end first. Close your legs and lie still for a few minutes. If the applicator will be reused, take it apart and wash it with warm water and mild soap, then dry it completely. Avoid having a bowel movement for at least 1 hour after inserting the suppository.
To ensure that you get a correct dose, measure the liquid forms of acetaminophen with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Shake the liquid well before measuring.
Never take more acetaminophen than is directed. The maximum amounts for adults are 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could be damaging to the liver. If you drink more than three alcoholic beverages per day, talk to your doctor before taking acetaminophen.

Use acetaminophen for up to 3 days for fever or up to 10 days for pain (or up to 5 days to treat a child's pain). If the symptoms do not improve, or if they get worse, stop using acetaminophen and see a doctor.

If you are treating a child, read the package carefully and use a pediatric form of the medication if possible. Talk to a doctor first if the child is younger than 2 years of age.
Store acetaminophen at room temperature away from heat, moisture, and the reach of children. The rectal suppositories can be stored at room temperature or in the refrigerator.


What happens if I miss a dose?

If you are taking acetaminophen on a regular schedule, take the missed dose as soon as you remember. Wait the prescribed amount of time or as directed in the package labeling before taking another dose. Do not take a double dose.

If you are taking acetaminophen on an as-needed basis, missing a dose is not usually a problem. Take the dose as soon as you remember, and do not take another dose for the amount of time prescribed or as directed in the package labeling.


What happens if I overdose?
Seek emergency medical attention.

Symptoms of an acetaminophen overdose include nausea, vomiting, diarrhea, abdominal pain, sweating, seizures, confusion, and an irregular heartbeat.


What should I avoid while taking acetaminophen?
Avoid alcohol during treatment with acetaminophen. Together, alcohol and acetaminophen can be damaging to the liver.

Be aware of the acetaminophen content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.


What are the possible side effects of acetaminophen?
If you experience any of the following rare but serious side effects, stop taking acetaminophen and seek emergency medical attention or contact your doctor immediately:

· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

· liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue);

· blood problems (easy or unusual bleeding or bruising).

Other, less serious side effects are not known to occur.

Side effects other than those listed here may occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect acetaminophen?

Be aware of the acetaminophen content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.

Acetaminophen may cause false urine glucose test results. Talk to your doctor if you have diabetes and you notice changes in your glucose levels while taking acetaminophen.

Other medications may interact with acetaminophen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products while taking acetaminophen.


Where can I get more information?

Your pharmacist has additional information about acetaminophen written for health professionals that you may read.

Childrens Panadol 1 - 5 Years Colourfree

acetaminophen (oral/ rectal)



Pronunciation: a see ta MIH no fen
Brand: Anacin-3 Maximum Strength, Childrens Tylenol, Tylenol, Tylenol Caplet, Tylenol Caplet Extra Strength, Tylenol Extended Release, Tylenol Extra Strength, Tylenol Gelcap Extra Strength, Tylenol Suspension


What is the most important information I should know about acetaminophen?

Use acetaminophen for up to 3 days for fever or up to 10 days for pain (or up to 5 days to treat a child's pain). If the symptoms do not improve, or if they get worse, stop using acetaminophen and see a doctor.
Avoid alcohol during treatment with acetaminophen. Together, alcohol and acetaminophen can be damaging to the liver.

Be aware of the acetaminophen content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.


What is acetaminophen?

Acetaminophen is a pain reliever and a fever reducer.

Acetaminophen is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.

Acetaminophen may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking acetaminophen?
Do not take acetaminophen without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease. You may not be able to take acetaminophen, or you may require a lower dose or special monitoring.

Before taking acetaminophen, tell your doctor if you have kidney or liver disease. You may not be able to take acetaminophen, or you may require a dosage adjustment or special monitoring during treatment if you have either of these conditions.

Acetaminophen has not been formally assigned to a pregnancy category by the FDA. It is routinely used for short term pain relief and fever in all stages of pregnancy. Acetaminophen is believed to be safe in pregnancy when used intermittently for short durations. Acetaminophen should only be given during pregnancy when need has been clearly established.

Acetaminophen passes into breast milk. It appears to be safe for use during breast-feeding but should be avoided if possible. Talk to your doctor before taking acetaminophen if you are breast-feeding a baby.

If you are treating a child, read the package carefully and use a pediatric form of the medication if possible. Talk to a doctor first if the child is younger than 2 years of age.


How should I take acetaminophen?

Take acetaminophen exactly as directed by your doctor or follow the instructions on the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each oral dose with a full glass of water.

Acetaminophen can be taken with or without food.
Wash your hands before and after using the rectal suppositories. Run the suppository under cold water or put it in the refrigerator for a few minutes before using it. Remove any wrapping from the suppository and moisten the suppository with cold water. Squat, stand, or lie down with one leg straight and the other bent, in a comfortable position that allows access to the rectal area. Use your finger, or the applicator if one is provided, to deposit the suppository as far as it will comfortably go into the rectum. Insert the narrow end first. Close your legs and lie still for a few minutes. If the applicator will be reused, take it apart and wash it with warm water and mild soap, then dry it completely. Avoid having a bowel movement for at least 1 hour after inserting the suppository.
To ensure that you get a correct dose, measure the liquid forms of acetaminophen with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Shake the liquid well before measuring.
Never take more acetaminophen than is directed. The maximum amounts for adults are 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could be damaging to the liver. If you drink more than three alcoholic beverages per day, talk to your doctor before taking acetaminophen.

Use acetaminophen for up to 3 days for fever or up to 10 days for pain (or up to 5 days to treat a child's pain). If the symptoms do not improve, or if they get worse, stop using acetaminophen and see a doctor.

If you are treating a child, read the package carefully and use a pediatric form of the medication if possible. Talk to a doctor first if the child is younger than 2 years of age.
Store acetaminophen at room temperature away from heat, moisture, and the reach of children. The rectal suppositories can be stored at room temperature or in the refrigerator.


What happens if I miss a dose?

If you are taking acetaminophen on a regular schedule, take the missed dose as soon as you remember. Wait the prescribed amount of time or as directed in the package labeling before taking another dose. Do not take a double dose.

If you are taking acetaminophen on an as-needed basis, missing a dose is not usually a problem. Take the dose as soon as you remember, and do not take another dose for the amount of time prescribed or as directed in the package labeling.


What happens if I overdose?
Seek emergency medical attention.

Symptoms of an acetaminophen overdose include nausea, vomiting, diarrhea, abdominal pain, sweating, seizures, confusion, and an irregular heartbeat.


What should I avoid while taking acetaminophen?
Avoid alcohol during treatment with acetaminophen. Together, alcohol and acetaminophen can be damaging to the liver.

Be aware of the acetaminophen content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.


What are the possible side effects of acetaminophen?
If you experience any of the following rare but serious side effects, stop taking acetaminophen and seek emergency medical attention or contact your doctor immediately:

· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

· liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue);

· blood problems (easy or unusual bleeding or bruising).

Other, less serious side effects are not known to occur.

Side effects other than those listed here may occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect acetaminophen?

Be aware of the acetaminophen content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.

Acetaminophen may cause false urine glucose test results. Talk to your doctor if you have diabetes and you notice changes in your glucose levels while taking acetaminophen.

Other medications may interact with acetaminophen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products while taking acetaminophen.


Where can I get more information?

Your pharmacist has additional information about acetaminophen written for health professionals that you may read.

Childrens Panadol 1 - 5 Years

chlorpheniramine, dextromethorphan, and pseudoephedrine



Pronunciation: klor feh NEER a meen, dex tro meh THOR fan, and soo doe eh FEH drin
Brand: Creomulsion Cough/Cold/Allergy, Nyquil Child Cough and Cold, Pediacare Cough and Cold, Pediacare Nightrest, Rescon-DM, Rhinosyn-DM, Robitussin Pediatric Night Relief, Triaminic Night Time, Triaminic Softchew Cold and Cough, Vicks 44M Pediatric


What is the most important information I should know about chlorpheniramine, dextromethorphan, and pseudoephedrine?
Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.
Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.


What is chlorpheniramine, dextromethorphan, and pseudoephedrine?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine, dextromethorphan, and pseudoephedrine is used to treat sneezing, runny or stuffy nose, cough, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.
Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking chlorpheniramine, dextromethorphan, and pseudoephedrine?
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, or pseudoephedrine, or if you have:

· kidney disease;

· diabetes;

· glaucoma;

· heart disease or high blood pressure;

· diabetes;

· a thyroid disorder;

· emphysema or chronic bronchitis;

· an enlarged prostate; or

· problems with urination.

If you have any of these conditions, you may not be able to use chlorpheniramine, dextromethorphan, and pseudoephedrine, or you may need a dosage adjustment or special tests during treatment.
This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Chlorpheniramine, dextromethorphan, and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.


How should I take chlorpheniramine, dextromethorphan, and pseudoephedrine?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.
Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.
Store the medication at room temperature away from moisture and heat.


What happens if I miss a dose?

Since cough and cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an overdose may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).


What should I avoid while taking chlorpheniramine, dextromethorphan, and pseudoephedrine?
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid using other medicines that make you sleepy (such as sleeping pills, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine, dextromethorphan, and pseudoephedrine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.
Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.


What are the possible side effects of chlorpheniramine, dextromethorphan, and pseudoephedrine?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

· fast, pounding, or uneven heartbeat, slow, shallow breathing;

· confusion, hallucinations, unusual thoughts or behavior;

· severe dizziness, anxiety, restless feeling, or nervousness;

· increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);

· easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

· urinating less than usual or not at all.

Keep taking the medication and talk to your doctor if you have any of these less serious side effects:

· dry mouth;

· nausea, stomach pain, constipation, mild loss of appetite, upset stomach;

· blurred vision;

· warmth, tingling, or redness under your skin;

· sleep problems (insomnia);

· restless or excitability (especially in children);

· skin rash or itching;

· dizziness, drowsiness, or headache;

· problems with memory or concentration; or

· ringing in your ears.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect chlorpheniramine, dextromethorphan, and pseudoephedrine?

Before taking this medication, tell your doctor if you are using any of the following drugs:

· a diuretic (water pill), or blood pressure medicine;

· medication to treat irritable bowel syndrome;

· bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), darifenacin (Enablex), or tolterodine (Detrol);

· aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);

· a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or

· antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

If you are using any of these drugs, you may not be able to use chlorpheniramine, dextromethorphan, and pseudoephedrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect chlorpheniramine, dextromethorphan, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


Where can I get more information?

Your pharmacist has information about chlorpheniramine, dextromethorphan, and pseudoephedrine written for health professionals that you may read.

Childrens NyQuil

chlorpheniramine, dextromethorphan, and pseudoephedrine



Pronunciation: klor feh NEER a meen, dex tro meh THOR fan, and soo doe eh FEH drin
Brand: Creomulsion Cough/Cold/Allergy, Nyquil Child Cough and Cold, Pediacare Cough and Cold, Pediacare Nightrest, Rescon-DM, Rhinosyn-DM, Robitussin Pediatric Night Relief, Triaminic Night Time, Triaminic Softchew Cold and Cough, Vicks 44M Pediatric


What is the most important information I should know about chlorpheniramine, dextromethorphan, and pseudoephedrine?
Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.
Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.


What is chlorpheniramine, dextromethorphan, and pseudoephedrine?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine, dextromethorphan, and pseudoephedrine is used to treat sneezing, runny or stuffy nose, cough, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.
Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking chlorpheniramine, dextromethorphan, and pseudoephedrine?
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, or pseudoephedrine, or if you have:

· kidney disease;

· diabetes;

· glaucoma;

· heart disease or high blood pressure;

· diabetes;

· a thyroid disorder;

· emphysema or chronic bronchitis;

· an enlarged prostate; or

· problems with urination.

If you have any of these conditions, you may not be able to use chlorpheniramine, dextromethorphan, and pseudoephedrine, or you may need a dosage adjustment or special tests during treatment.
This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Chlorpheniramine, dextromethorphan, and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.


How should I take chlorpheniramine, dextromethorphan, and pseudoephedrine?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.
Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.
Store the medication at room temperature away from moisture and heat.


What happens if I miss a dose?

Since cough and cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an overdose may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).


What should I avoid while taking chlorpheniramine, dextromethorphan, and pseudoephedrine?
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid using other medicines that make you sleepy (such as sleeping pills, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine, dextromethorphan, and pseudoephedrine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.
Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.


What are the possible side effects of chlorpheniramine, dextromethorphan, and pseudoephedrine?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

· fast, pounding, or uneven heartbeat, slow, shallow breathing;

· confusion, hallucinations, unusual thoughts or behavior;

· severe dizziness, anxiety, restless feeling, or nervousness;

· increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);

· easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

· urinating less than usual or not at all.

Keep taking the medication and talk to your doctor if you have any of these less serious side effects:

· dry mouth;

· nausea, stomach pain, constipation, mild loss of appetite, upset stomach;

· blurred vision;

· warmth, tingling, or redness under your skin;

· sleep problems (insomnia);

· restless or excitability (especially in children);

· skin rash or itching;

· dizziness, drowsiness, or headache;

· problems with memory or concentration; or

· ringing in your ears.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect chlorpheniramine, dextromethorphan, and pseudoephedrine?

Before taking this medication, tell your doctor if you are using any of the following drugs:

· a diuretic (water pill), or blood pressure medicine;

· medication to treat irritable bowel syndrome;

· bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), darifenacin (Enablex), or tolterodine (Detrol);

· aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);

· a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or

· antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

If you are using any of these drugs, you may not be able to use chlorpheniramine, dextromethorphan, and pseudoephedrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect chlorpheniramine, dextromethorphan, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


Where can I get more information?

Your pharmacist has information about chlorpheniramine, dextromethorphan, and pseudoephedrine written for health professionals that you may read